Locating and Isolating Neurological Disorders in MRI Datasets Using Hardware-Accelerated Delaunay Triangulation

Authors

  • A. M. Adeshina Faculty of Information Science and Technology, Multimedia University, Malaysia
  • S. O. Kareem High Performance Computing Research Laboratory, Nigeria
Volume: 16 | Issue: 2 | Pages: 33611-33619 | April 2026 | https://doi.org/10.48084/etasr.13569

Abstract

Parkinson's disease and stroke are among the deadliest progressive neurological disorders affecting movement. Researchers have attributed the increasing prevalence of Parkinson's disease to the aging global population, making it the fastest-growing neurodegenerative disease. Interdisciplinary research in computer science and bioengineering frequently finds alternative and improved techniques that can greatly assist in the diagnosis and management of Parkinson's disease. Studies to date still confirm that Parkinson's disease is challenging to diagnose, as there are no specific tests to confirm the disease, and many symptoms overlap with those of other neurodegenerative disorders, such as essential tremor, a condition that causes involuntary and rhythmic shaking similar to that observed in Parkinson's disease. Connectomes and artificial intelligence have recently been examined for computer-assisted disease diagnosis and therapy management. Connectomes map and analyze neural linkages within the human nervous system, providing a viable approach for diagnosing brain diseases requiring detailed assessment of vascular structures. This study proposes a hardware-accelerated brain connectomic framework for locating and isolating possible neurological disorders in Magnetic Resonance Imaging (MRI) datasets using the Delaunay triangulation algorithm. The framework was implemented using the Microsoft .NET environment, primarily in C# and Visual Basic (VB), and integrated with hardware acceleration for enhanced processing. The connectomic framework was evaluated using Magnetic Resonance (MR) brain images from the Department of Surgery, University of North Carolina, United States, which mostly contained healthy datasets and certain brain abnormalities. Notably, the framework was not only able to successfully depict the connectomes of the datasets but also achieved processing times of less than 17 s for datasets containing more than 300 images. Moreover, the connectomic framework is considered resourceful in revealing the vascular structures in MR brain images, irrespective of the captured neurological disorders, with all features optimized for web and browser compatibility.

Keywords:

brain abnormalities, brain diagnosis, connectomes, hardware acceleration

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References

X. D. Arsiwalla et al., "Network dynamics with BrainX3: a large-scale simulation of the human brain network with real-time interaction," Frontiers in Neuroinformatics, vol. 9, Feb. 2015, Art. no. 2. DOI: https://doi.org/10.3389/fninf.2015.00002

N. Opel et al., "White matter microstructure mediates the association between physical fitness and cognition in healthy, young adults," Scientific Reports, vol. 9, no. 1, Sept. 2019, Art. no. 12885. DOI: https://doi.org/10.1038/s41598-019-49301-y

S. J. Forkel, P. Friedrich, M. Thiebaut de Schotten, and H. Howells, "White matter variability, cognition, and disorders: a systematic review," Brain Structure and Function, vol. 227, no. 2, pp. 529–544, Mar. 2022. DOI: https://doi.org/10.1007/s00429-021-02382-w

F. Zhang et al., "Whole brain white matter connectivity analysis using machine learning: An application to autism," NeuroImage, vol. 172, pp. 826–837, May 2018. DOI: https://doi.org/10.1016/j.neuroimage.2017.10.029

F.-C. Yeh et al., "Quantifying Differences and Similarities in Whole-Brain White Matter Architecture Using Local Connectome Fingerprints," Plos Computational Biology, vol. 12, no. 11, Nov. 2016, Art. no. e1005203. DOI: https://doi.org/10.1371/journal.pcbi.1005203

N. Zuo et al., "White Matter Abnormalities in Major Depression: A Tract-Based Spatial Statistics and Rumination Study," Plos One, vol. 7, no. 5, May 2012, Art. no. e37561. DOI: https://doi.org/10.1371/journal.pone.0037561

A. M. Adeshina and R. Hashim, "ConnectViz: Accelerated Approach for Brain Structural Connectivity Using Delaunay Triangulation," Interdisciplinary Sciences: Computational Life Sciences, vol. 8, no. 1, pp. 53–64, Mar. 2016. DOI: https://doi.org/10.1007/s12539-015-0274-9

D. A. Keim, J. Kohlhammer, G. Ellis, and F. Mansmann, Mastering the Information Age Solving Problems with Visual Analytics. Goslar, Germany: Eurographics Association, 2010.

J. Beyer, M. Hadwiger, and H. Pfister, "A Survey of GPU-Based Large-Scale Volume Visualization," in Proceedings of The Eurographics Conference on Visualization, Swansea, Wales, 2014.

C. Silvano et al., "A Survey on Deep Learning Hardware Accelerators for Heterogeneous HPC Platforms," ACM Comput. Surv., vol. 57, no. 11, June 2025, Art. no. 286. DOI: https://doi.org/10.1145/3729215

J. Beyer, M. Hadwiger, and H. Pfister, "State-of-the-Art in GPU-Based Large-Scale Volume Visualization," Computer Graphics Forum, vol. 34, no. 8, pp. 13–37, Dec. 2015. DOI: https://doi.org/10.1111/cgf.12605

Q. Min, Z. Wang, and N. Liu, "An Evaluation of HTML5 and WebGL for Medical Imaging Applications," Journal of Healthcare Engineering, vol. 2018, no. 1, Aug. 2018, Art. no. 1592821. DOI: https://doi.org/10.1155/2018/1592821

I. Isikay, E. Cekic, B. Baylarov, O. Tunc, and S. Hanalioglu, "Narrative review of patient-specific 3D visualization and reality technologies in skull base neurosurgery: enhancements in surgical training, planning, and navigation," Frontiers in Surgery, vol. 11, July 2024, Art. no. 1427844. DOI: https://doi.org/10.3389/fsurg.2024.1427844

S. Arun, E. R. Sykes, and S. Tanbeer, "RemoteHealthConnect: Innovating patient monitoring with wearable technology and custom visualization," Digital Health, vol. 10, Sept. 2024, Art. no. 20552076241300748. DOI: https://doi.org/10.1177/20552076241300748

E. Bullitt et al., "The effects of healthy aging on intracerebral blood vessels visualized by magnetic resonance angiography," Neurobiology of aging, vol. 31, no. 2, pp. 290–300, Feb. 2010. DOI: https://doi.org/10.1016/j.neurobiolaging.2008.03.022

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How to Cite

[1]
A. M. Adeshina and S. O. Kareem, “Locating and Isolating Neurological Disorders in MRI Datasets Using Hardware-Accelerated Delaunay Triangulation”, Eng. Technol. Appl. Sci. Res., vol. 16, no. 2, pp. 33611–33619, Apr. 2026.

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